What is Selank?
Selank is a synthetic heptapeptide built from tuftsin, the tetrapeptide Thr-Lys-Pro-Arg, extended at the C-terminus with Pro-Gly-Pro. As with Semax, the proline-rich extension improves its stability against peptidases.
Selank structure and sequence
The sequence is Thr-Lys-Pro-Arg-Pro-Gly-Pro, molecular formula C33H57N11O9, molecular weight 751.9 Da. With two basic residues and three prolines it is very water soluble and elutes early on reversed phase chromatography.
Where this material appears in the literature
Published work on Selank is preclinical and in vitro, in neurobiology research and studies of tuftsin analogs. Revyon Technologies supplies the material for laboratory investigation of that kind and makes no claim about its effects in any living subject.
Related material in the catalog
Other neurobiology research peptides include Semax, DSIP, Pinealon, all listed under neurobiology research.
Analysis and certification
Every lot is analyzed by an independent laboratory before release, using RP-HPLC for purity and LC-MS for identity confirmation. The certificate of analysis is published against the lot number rather than against the product page, so each report covers one specific production lot. Browse the COA library for the latest COA for this product.
Purity specification
Lots are released against a ≥98% purity specification, determined by RP-HPLC peak area. A specification is a release threshold, not a description of every lot. The measured figure for the lot you receive is stated on its certificate of analysis and may sit above the specification.
Where a measured figure and the specification differ, the certificate is the record that applies to your material. Analytical figures relate to the lot they are published against and carry no implication of suitability for any purpose beyond laboratory research.
Research use only
Revyon Technologies supplies this material as a reference compound for in-vitro laboratory research. It is not supplied for any use in humans or animals, it is not a drug, dietary supplement, food or cosmetic, it has not been evaluated or approved by the FDA, and nothing on this page describes or implies any such use. Sale is restricted to persons aged 21 or over who are qualified researchers or who purchase on behalf of a research institution, laboratory or business.
| Compound |
Selank |
| Also known as |
Tuftsin-Pro-Gly-Pro |
| Class |
Synthetic heptapeptide |
| Amino acids |
7 |
| Sequence |
Thr-Lys-Pro-Arg-Pro-Gly-Pro |
| Molecular formula |
C33H57N11O9 |
| Molecular weight |
751.9 Da |
| CAS number |
129954-34-3 |
| Appearance |
White to off white lyophilized powder |
| Purity specification |
≥98% |
| Purity method |
RP-HPLC |
| Identity method |
LC-MS |
| Solubility |
Soluble in sterile water and aqueous buffers for analytical preparation |
| Labeled quantity |
10 mg per vial |
| Container |
Crimp-sealed glass vial with tamper-evident cap |
Characterization. Values above describe the compound as supplied. The figures for the lot you receive, including measured purity, are stated on its certificate of analysis.
How this material is tested
Two separate analyses are carried out on every lot before release, and both appear on the certificate.
- RP-HPLC, for purity. Reversed phase high performance liquid chromatography separates the material by hydrophobicity. The main peak is integrated against total peak area, and that ratio is the purity figure reported on the certificate.
- LC-MS, for identity. Liquid chromatography coupled to mass spectrometry confirms that the mass of the main peak matches the expected mass for the compound, which is what distinguishes the correct material from a closely related one.
A complete certificate carries the compound name, the lot number, the test date, the method, the measured purity and the name of the laboratory. If any of those is missing, contact us before using the material.
Storing Selank
As a dry lyophilized solid, Selank is stable for the duration of normal transit. On arrival, move the sealed vial into freezer storage at −20°C or below, kept dry and protected from light and moisture. Returned promptly to those conditions, the dry solid is the most stable form this material takes.
Preparing stock solutions
Prepare stock solutions in sterile water or an appropriate aqueous buffer at a concentration suited to your assay, expressed in mg/mL. Allow the vial to reach room temperature before opening, add solvent down the vial wall rather than directly onto the solid, and let the material dissolve without vigorous agitation. Selank dissolves readily in water at the concentrations used for analytical work.
Solutions are less stable than the lyophilized solid. Prepare close to the point of use, hold at 2 to 8°C for short periods only, and aliquot before freezing so that repeated freeze and thaw cycles are avoided.
On arrival
Check that the container is intact and sealed, and that the compound name and labeled quantity match your order. If anything does not match, or the packaging has clearly failed in transit, contact us before using the material. Report any problem within 7 days of delivery, with your order number, the lot number and photos, as set out in our shipping and returns policy.
Handling and disposal
Assess the hazards of this material before handling it and use appropriate controls and protective equipment. It has not been fully characterized toxicologically and should be treated as potentially hazardous. Anyone handling it should be trained for the work.
Dispose of unused material, containers and packaging lawfully and in line with your institution's waste procedures.
Record keeping
Record the lot number in your notes at the point of first use, alongside the date the container was opened and the concentration of any stock prepared. Certificates are published against the lot number rather than the product, so the lot number is the only reliable link between your results and the analytical data for the material that produced them. If a question arises about a result months later, that link is what keeps the work auditable.